De Soto, MO
Population 6,452 · Missouri
About De Soto, MO
De Soto is a small community in Missouri with a population of 6,452 residents. The median household income is $46,181 per year, which is below the national average. The median age in De Soto is 32.6 years.
Housing in De Soto has a median home value of $144,000 and median monthly rent of $828. Of the 3,075 total housing units, the majority are owner-occupied, with 1,617 owner-occupied and 1,129 renter-occupied units.
The unemployment rate in De Soto is 5.2% and the poverty rate is 14.7%. 11.3% of residents hold a bachelor's degree or higher. The average commute time is 35.7 minutes.
Cost of Living in De Soto, MO
Compared to national averages, De Soto has a median household income of $46,181 (39% below the national median of $75,149). Home values average $144,000, which is 41% below the national median. Monthly rent at $828 is 29% below the US average of $1,163. Within Missouri, De Soto's income is 24% below the state average of $61,047, and home values are 5% below the state median of $150,786.
Why Live in De Soto, MO?
De Soto offers affordable housing with a median home value of $144,000, below the US average of $244,900, and rent that’s lower than the national average at $828/month.
Potential considerations include median household income ($46,181) that falls below the national average. However, De Soto’s smaller community size offers a quieter lifestyle and tight-knit neighborhoods.
De Soto has a population of 6,452 with a median age of 32.6 years. Compare De Soto with other cities to see how it stacks up, or explore all cities in Missouri.
Similar Cities Near De Soto
Cities in Missouri with a similar population size.
| City | Population | Median Income | Home Value | |
|---|---|---|---|---|
| Willard | 6,418 | $87,204 | $204,300 | Compare |
| Sullivan | 6,355 | $60,137 | $153,100 | Compare |
| St. John | 6,562 | $50,429 | $96,900 | Compare |
| Shrewsbury | 6,328 | $84,942 | $266,600 | Compare |
| Black Jack | 6,606 | $65,920 | $187,600 | Compare |
| Bonne Terre | 6,773 | $39,767 | $120,400 | Compare |
| Glendale | 6,111 | $168,750 | $510,100 | Compare |
| Battlefield | 6,095 | $87,414 | $207,100 | Compare |
Demographics
Racial & Ethnic Composition
Economy & Education
Housing
Other Cities in Missouri
Data source: US Census Bureau ACS 5-Year Estimates. Last updated: 2026-04-05.
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Frequently Asked Questions about De Soto
What is the population of De Soto, MO?
The population of De Soto, MO is 6,452 according to the latest Census data.
What is the median household income in De Soto?
The median household income in De Soto, MO is $46,181 per year.
What is the median home value in De Soto?
The median home value in De Soto, MO is $144,000.
What is the average rent in De Soto?
The median monthly rent in De Soto, MO is $828.
What is the unemployment rate in De Soto?
The unemployment rate in De Soto, MO is 5.2%.